Q:

What is a geometric dilution method?

A:

Quick Answer

Geometric dilution is a pharmaceutical process that thoroughly mixes a small amount of a drug with an appropriate amount of a diluent, an inert substance that thins or binds the drug. It ensures equal distribution of the drug throughout the resulting compound, according to the UNC Eshelman School of Pharmacy.

Continue Reading

Full Answer

The method used depends on the types of substances used, such as a fluid or powder, and the form, such as an ointment or tablet, of the compound. Two commonly used geometric dilution methods include trituration, which can be used to combine powders or mix a powder into an ointment, and the liquid aliquot method, which involves combining fluids to create a solution, as explained by the UNC Eshelman School of Pharmacy.

Trituration, which involves reducing a substance to particle size, requires the use of a mortar and pestle to grind together equal parts of substances in small-batch quantities, adding the same amount of each substance and repeating the process until the entire amount of both substances has been mixed together. The liquid aliquot method involves dissolving a quantity of the drug in a small quantity of an appropriate solvent, often water or alcohol, to reach a desired volume, according to the UNC Eshelman School of Pharmacy. The aliquot, which is the desired amount of the concentrated drug solution, is then added to a larger amount of solution to make up the total volume of the prescription.

Learn more about Solutions & Mixtures

Related Questions

  • Q:

    What is a colloid?

    A:

    A colloid is a substance that appears to be a singular component but is actually made up of two different components. Milk is colloid made up of butter fat and water.

    Full Answer >
    Filed Under:
  • Q:

    What is a hypertonic environment?

    A:

    A hypertonic environment is one in which the concentration of a solution's dissolved substance is greater than the concentration of the dissolved substance in the solution compared. If a cell is placed in a hypertonic environment, the cell membrane works to achieve equal concentrations on each side of the membrane.

    Full Answer >
    Filed Under:
  • Q:

    What does "soluble" mean in science?

    A:

    When something can be dissolved or liquefied in the presence of another substance, it is considered soluble by scientific standards. The degree of solubility can vary. Substances can be completely insoluble, soluble only under certain conditions or extremely soluble under most conditions.

    Full Answer >
    Filed Under:
  • Q:

    What are nonpolar solutes?

    A:

    A nonpolar solute is a substance that has no dipole elements and is dissolved in a solution. Many of these solutes are organic chemicals dissolved in organic liquids. Solutions follow the rule of like dissolves like, so nonpolar solutes are difficult to dissolve in polar solvents, such as water.

    Full Answer >
    Filed Under:

Explore