The most popular homemade natural tranquilizer is Cal Mag. It is made by mixing calcium gluconate, magnesium carbonate, cider vinegar and boiling water. There are ancient Chinese remedies that have tranquilizing effects and modern medicines that serve the same purpose.
Cal Mag is made by mixing one tablespoon of calcium gluconate in a beaker or glass cup with 1/2 teaspoon of magnesium carbonate and one tablespoon of cider vinegar with at least 5 percent acidity. Add approximately 120 milliliters of boiling water, and stir until the powder dissolves. Put a metal spoon in the beaker or glass cup to avoid cracking, then fill the remainder of the glass with lukewarm or cold water. Keep refrigerated.
Zhu Sha An Shen Wan is an ancient Chinese formula for a mind tranquilizing pill. To make it, refine 15 milligrams of cinnabaris with water, and mix with 18 grams of Cuptis, 16 grams of roasted lienrice runt, 8 grams of dried rehmannia rou and 8 grams of Chinese angelican root. Use all ingredients in a powder form to make a pill.
Meprobamate is a white, bitter powder used as a tranquilizer for treating anxiety, tension and skeletal muscle spasm. Benzodiazepines are often used in medicine as tranquilizers as well.