The EGFR, or estimated glomerular filtration rate, is calculated the same for all adults and is not determined by the race of an individual. The EGFR is a test that measures the amount of serum creatinine found in the urine. A normal range for adults with normal kidney function is 0.8 to 1.3 milligrams per deciliter for males and 0.6 to 1.1 milligram per deciliter for females.
Several things may influence the EGFR level in adults. Young adults with large muscle mass may have a higher serum creatinine level than elderly adults, as creatinine production is based on total muscle mass. Certain medications also may increase the production of creatinine in the body.
An EGFR is used to detect chronic kidney disease and to track the progress of treatments used. A 24-hour creatinine-clearance test is another test used in the treatment of chronic kidney disease, but the EGFR test produces more reliable results.
Chronic kidney disease is common in individuals with hypertension, diabetes, systemic infections and autoimmune diseases. Individuals who have a family history of chronic kidney disease are also at risk for developing the disease, and regular testing of creatinine levels is essential in prevention and treatment. An EGFR is not a suitable test for women who are pregnant, people who have an acute illness or people who have other serious medical comorbidities, as the test may not be a reliable indicator of chronic kidney disease in these populations.