What Is a Mechanical Barrier in the Immune System?

A mechanical barrier in the immune system is a primary line of defense, which physically impedes the entry of foreign particles that may harm the body. Common mechanical barriers include the skin, mucous membranes and the cornea.

The immune system is a complex series of protective measures that defends the body against infectious microorganisms, cancer cells or transplanted tissues or organs. An immune response is triggered when the immune system detects foreign invaders. This auto-response combats potentially pathogenic elements.

The immune system comprises defensive mechanisms such mechanical barriers, white blood cells and molecular components, such as cytokines, complement proteins and antibodies. Mechanical barriers, otherwise known as physical barriers, are considered as the most crucial line of defense.