What Do White Spots Mean in a Bone Scan?

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White spots show up on a bone scan around the dark spots, which indicate an increased accumulation of radioactive material from the scan. In other words, the white areas surround the dark areas that indicate various medical problems, including cancer and arthritis, depending upon where the dark spots appear. MedlinePlus states that an abnormal bone scan shows hot spots and/or cold spots in comparison to surrounding bone.