How Do You Treat Sinus Drainage at Night?

By Staff WriterLast Updated Mar 26, 2020 12:10:23 PM ET

To keep mucus from draining down the throat during the night, taking an antihistamine or decongestant can dry the sinuses. Other options include taking a mucus-thinning medication to reduce irritation from the drainage or propping pillows at night to keep mucus out of the back of the throat, notes WebMD.