Hepatitis B surface antibody titers of greater than or equal to 12 milli-units per milliliter indicate immunity to hepatitis B, states Mayo Medical Laboratories. Titers less than 5 milli-international units per milliliter indicate the lack of an immune response. Titer results do not distinguish between infection or immunization responses.
Experts recommend repeat testing for titer results between 5 and 12 milli-international units per milliliter, says Mayo Medical Laboratories. The hepatitis B surface antigen appears in the body as early as six weeks after infection, followed by antibodies against the surface antigen in one to two months. Antibodies also appear after vaccination.
Hepatitis B spreads through infected bodily fluids such as blood, and becomes chronic in some individuals. Chronic infection sometimes progresses to liver cirrhosis or liver cancer, states Mayo Medical Laboratories.