Symptoms of lytic bone lesions vary since many different diseases can cause them. Typical symptoms include pain, pathologic bone fractures and high blood calcium, according to MedicineNet. Pathologic bone fractures occur when disease weakens and breaks the bone.
A lytic lesion is a general term for an area of bone weakened by disease, states The National Cancer Institute. The types of diseases that weaken the bone can be benign or malignant.
There are many varieties of benign bone tumors and cysts, explains the Cleveland Clinic. Some benign conditions such as bone cysts can be asymptomatic, while others may include bone pain, swelling and fractures. Malignant bone cancers such as osteosarcoma commonly present with bone pain as the main symptom.