Is Stage 4 Cancer the Highest Stage of Cancer?

Referred to as advanced or metastatic cancer, Stage 4 cancer responds poorly to therapies like radiotherapy or surgery unless the metastasis is singular and the tumor has spread to a precise, accessible position, notes Oasis of Hope. Some cancers at this point can initially be treated effectively with chemotherapy; however, most tumors eventually grow back in a way that is less responsive to chemotherapy.