Irritation of the mucous membranes near the oral cavity site represent a possible side effect of an allergic reaction to acrylic dentures, according to the National Institutes of Health. Soaking dentures in hot water for one hour may minimize these reactions.
The mouth and lips may also become inflamed and swollen due to acrylic dentures, notes the National Institutes of Health. Doctors and dentists can perform skin patch tests to determine if the patient is allergic to materials in acrylic dentures. Allergic reactions to methyl methacrylate and 2-hydroxyethyl methacrylate are the most common allergies observed in these types of cases, although any allergic reaction to acrylic dentures is rare.
More severe allergic reactions to acrylic dentures include fatigue, pain, food allergies, headaches and sinusitis, notes the International Center for Nutritional Research. Other dental materials such as crowns, fillings and denture frameworks may cause these types of reactions. Toxicity of dental materials could be responsible for allergies to dental implants.
Methyl methacrylate, a substance widely used in dental and medical applications, may cause lesions and abnormalities in several organs, according to the National Institutes of Health. Irritation can occur on the skin, eyes and mucous membranes. Asthma, neuropathy, nervous system disturbances, fertility problems and liver toxicity may result from the body's reaction to methyl methacrylate.