A blister from a fire ant bit should not be popped. Popping the blister opens the wound and risks infection, according to Healthline. Treat fire ant stings with soap and water, and use ice compresses and topical ointments for pain.
Fire ants swarm when intruded upon and sting repeatedly, explains Healthline. Their stings appear as groups of swollen red spots that form blisters on the top. The stings cause pain and itching that last up to one week. Treat the affected area by cleansing thoroughly with soap and water and regularly applying ice packs to reduce pain and inflammation. If an allergic reaction is suspected, seek immediate medical help.