A puzzle piece tattoo symbolizes autism. The puzzle piece logo is the universal symbol for autism, and many people get this logo, or some form of it, inked onto their skin to show support for a loved one.
The puzzle piece design was originally used by autism advocacy groups to symbolize an autistic person's struggles to fit in with others. Many puzzle piece tattoos feature interlocking pieces in different bright, bold colors to represent the diverse and unique ways each individual with Autism is affected by the disease. Blue is the traditional color for autism awareness, so blue puzzle piece tattoos are most likely to be in honor of autism.
Puzzle piece tattoos can also have other meanings. Some couples or friends get matching puzzle piece tattoos to symbolize their bond to one another, while others simply like the design.