A 12-ounce can of Sprite contains 33 grams of sugar, according to Self Nutritional Data. A 16-ounce bottle of the soft drink has 44 grams of sugar.
A 12-ounce bottle of Sprite contains 37 grams of carbohydrate, about 12 percent of the recommended daily value, and 33 of those carbohydrate grams are from sugar. The 16-ounce bottle of Sprite contains 50 grams of carbohydrates total, with 44 of those coming from sugars. The 12-ounce size is 148 calories, while a 16-ounce bottle of Sprite contains 197 calories. Since a teaspoon of sugar contains about 4 grams of sugar, a 12-ounce bottle of Sprite contains the equivalent of more than 8 teaspoons of sugar.