What Does a Low SEG Level Mean on a Blood Test?

Blood tests showing a low SEG, or ‘segmental neutrophil level,’ often indicate an infection or sepsis. Segmental neutrophils are the primary white blood cells responsible for fighting infection, especially those caused by fungi and bacteria.

When an infection is present in the body, neutrophils cluster in the area of infection, leaving fewer neutrophils circulating in the blood.

Neutropenia is the condition that describes abnormally low levels of segmental neutrophils. Individuals dropping to 500 neutrophils per microliter of blood pose the risk of infection from even the most common bacteria found in the mouth and intestines.

Neutropenia is treated by diagnosing and treating the underlying infection responsible for the low amount.