How Long Do You Cook Pork Loin in the Oven?

By Staff WriterLast Updated April 13, 2020

Cook boneless pork loin in the oven at 350 F, with 26 to 28 minutes allotted for a roast smaller than 2 pounds and 20 to 25 minutes allotted for a roast that is 3 to 5 pounds. The final internal temperature should be at least 145 F.

For example, a boneless roast that is 4 pounds would be ready to serve after one hour and 20 minutes to one hour and 40 minutes in a 350 F oven. For a slightly more well-done roast, leave it in the oven a bit longer, up to an internal temperature of 165 F.