What Is a Good Substitute for Horseradish?

Other substitutes include grated ginger or spicy mustard. While these ingredients can provide a similar level of heat, they also alter the flavor of the recipe. When a recipe calls for fresh horseradish, commercially-prepared horseradish or horseradish sauce, which is made with a sour cream or mayonnaise base, can be substituted. Most grocery stores place prepared horseradish in the deli or meat department.