The drug Pamabrom is the most commonly used over-the-counter diuretic and is recommended as safe and mild by NetWellness. Diurex is a brand-name Pamabrom-based medication, according to Everyday Health.
Pamabrom is used to treat conditions like hypertension and edema by removing excess water and salt from the bloodstream. Women often take Diurex to relieve menstrual symptoms like temporary weight gain and bloating due to water retention. It is recommended that this medication be used only after consulting with a physician, because some medical conditions, such as kidney disease, may be affected by its use. Some people are allergic to Pamabrom.