Do Glucosamine and Chondroitin Affect Blood Pressure?

Glucosamine and chondroitin may affect blood pressure, states Mayo Clinic. Glucosamine may cause heart palpitations and an irregular heart rate, and chondroitin may increase the heart rate. People with heart conditions or who take medications, supplements or herbs related to blood pressure should be cautious when using glucosamine and chondroitin.