What Is the Correct Dosage for a Vitamin B-12 Injection?

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The correct dosage for vitamin B-12 injections depends on the patient’s age and the reason for the injection, states Mayo Clinic. For adults with vitamin B-12 deficiencies, doctors often prescribe 1,000 microgram intramuscular injections of cobalamin daily for 10 days, and then reduce the dosage to weekly for four weeks.

After four weeks, patients with vitamin B-12 deficiencies can expect to take B-12 injections permanently, explains Mayo Clinic.

Doctors treating adult depression administer 1 milligram injections of cyanocobalamin weekly for four weeks. For mental performance, doctors prescribe one 1,000 microgram vitamin B-12 injection daily for five days, followed by one monthly injection of 1,000 micrograms for five months. Doctors also administer 1,000 microgram injections weekly for four weeks, or once a month for six months, notes Mayo Clinic.