What Causes Pain Above the Navel?

By Staff WriterLast Updated Mar 25, 2020 6:55:01 AM ET

While abdominal pain has many causes, Mayo Clinic states that pain located in the center of the abdomen is often caused by appendicitis, intestinal obstruction, pancreatitis, mesenteric thrombosis and thoracic aortic aneurysm. High levels of ketones or waste products in the blood can also cause pain above the navel.