What Can Cause a Blood Clot in the Liver?

The most common causes of blood clots in the liver include blood disorders, liver trauma, liver cancer, infections, pregnancy, autoimmune disorders and inflammatory disorders, according to Healthline. Certain medications, such as birth control pills and immunosuppressive drugs, also cause blood clots in the liver.

Hepatic vein thrombosis, or HVT, is the medical name for a blockage in the veins of the liver caused by a blood clot, explains Healthline. The flow of blood to the heart coming from the liver is impeded, and the liver may be harmed if it is unable to get sufficient oxygen.

The most common symptom of HVT is an enlarged liver and a bulidup of fluids within the abdomen. Other symptoms include vomiting blood, nausea, weight loss, pain in the abdomen, jaundice, and swelling of the legs and feet, notes Healthline.