Puppies should get their first combination vaccine shows when they are between six and seven weeks old. These shots include vaccines for distemper, hepatitis, coronavirus, parainfluenze and paraovirus.
Some resources suggest that it’s better to wait until puppies are seven to eight weeks old before an owner gets them their first shots. Generally, veterinarians recommend that puppies receive their second combination vaccine shot at around nine weeks old. The third combination injection should come when they are about 12 weeks old. Sometimes a Lyme's disease vaccine is recommended at this time as well. The Lyme's disease vaccine requires a second injection two weeks later, and veterinarians often recommend that the Lyme's disease vaccine be repeated once per year after that. The last combination vaccine is usually administered when a puppy is 16 weeks old. The rabies vaccine may be given between 12 and 16 weeks. There are usually local laws that govern when this shot should be given since rabies may be transmitted to humans. It’s important for pet owners to check local laws in order to make sure their puppy gets this shot at the right time. There are some types of dogs that may need additional shots as well, such as Dobermans, which need two Parvo vaccines.