Pills dissolve in the stomach when they are broken down by stomach acid. According to the Merck Manual, different dosages of drugs dissolve or dissolute inside the stomach based on the properties of their physical, outer shell. For example, tablets that have enteric coatings, such as aspirin, are able to withstand the low pH of the stomach, however, pills that do not have this coating will break down in the same conditions.Continue Reading
The human stomach is generally an acidic environment with pH levels ranking between one and two. Medication that dissolves in pH one or two is processed to make its way into the bloodstream without having to go through the intestines. Not all drugs are meant to be dissolved in the stomach, because the acidic environment can interfere with the drug's potency. If a medication does not dissolve in the stomach, it is usually the job of the juices inside the large intestine to break it down, before it is further metabolized.
The rate and location where a drug is released in the body is important when considering the toxicity of the drug. According to Ansel's Pharmaceutical Dosage Forms and Drug Delivery Systems, a rapid rate of drug absorption is not considered ideal; and, it may promote further health implications, such as eroding the lining of the stomach.Learn more about Medications & Vitamins
Zantac, also called ranitidine, is a histamine receptor blocker used to treat conditions that involve problems with stomach acid, explains Drugs.com. Stomach ulcers, heartburn and gastroesophageal reflux disease are common conditions treated by Zantac, while Zollinger-Ellison syndrome and gastroparesis are rarer conditions that may improve with the use of Zantac.Full Answer >
According to the International Foundation for Functional Gastrointestinal Disorders, the best antacid for reducing stomach acid is calcium carbonate, which is the primary ingredient in brands such as Tums and Titralac. Other antacids include sodium bicarbonate, aluminum hydroxide and magnesium hydroxide.Full Answer >
Treatment for a peptic ulcer, which affects the stomach, small intestine or esophagus, includes antibiotic medicines that eliminate H. pylori, drugs that block acid production, and antacids that relieve pain and neutralize stomach acid, according to Mayo Clinic. Doctors may also recommend cytoprotective agents, which protect the stomach lining.Full Answer >
Sodium bicarbonate, the active ingredient in baking soda, works as a temporary antacid to reduce stomach acid and reduce heartburn, upset stomach and indigestion, according to WebMD. With a doctor’s prescription, patients take it to reduce the acid in urine, helping to prevent kidney stones and gout.Full Answer >