Stage IV squamous cell carcinoma, like other stage IV cancers, causes fatigue, pain, headache, weight loss, nausea and vomiting, confusion and anemia, reports the American Cancer Society. Stage IV indicates that cancer is spreading to lymph nodes, bones and other organs, says the Cancer Treatment Centers of America.
Squamous cell carcinoma of the skin most frequently occurs in areas exposed to sunlight, but can occur anywhere, says the Mayo Clinic. Initial symptoms include a red nodule, a scaly sore, a newly opened sore, a sore or rough spot in the mouth or a raised spot on a healed scar.
In late stage cancer patients, anemia is common because of the cancer itself and because of the treatments, says the American Cancer Institute. Confusion can occur due to pain, medication or changes in blood chemistry. Cancer, medication, anemia and lower food intake may cause fatigue in cancer patients. Nausea and vomiting during late stage cancer often result from the treatment and usually resolve themselves. Pain is common in advanced stage cancer due to the spread of the cancer, and it is often controlled by cancer treatments. Some cancer patients suffer a loss of appetite that leads to weight loss. Advanced stage cancer can also inhibit the absorption of nutrients from food.