The symptoms of a Clostridium difficile, or C. diff, infection include watery diarrhea three or more times a day, abdominal pain or tenderness, blood or pus in the stool, fever, loss of appetite and weight loss, according to WebMD. The severity of the symptoms ranges from mild to life-threatening.
A bacterial imbalance in the digestive tract causes Clostridium difficile, says WebMD. C. diff bacteria can be relatively harmless in a healthy gastrointestinal tract. When an alteration in the normal intestinal flora occurs, however, C. diff bacteria can overgrow and release toxins that attack and irritate the intestinal lining. The most frequent cause of an overgrowth of C. diff bacteria is the use of broad-spectrum antibiotics, such as fluoroquinolones, cephalosporins, clindamycin and penicillins, notes the Mayo Clinic.