What Is Stage 3 Lymphoma Cancer?

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In stage 3 lymphoma, cancer is present in the lymph nodes on both sides of the diaphragm, explains Cancer Research UK. Lymphoma cancer, Hodgkin and non-Hodgkin, is categorized into four stages denoted by Arabic numbers 1, 2, 3 and 4 based on the disease’s location and spread.

Both Hodgkin and non-Hodgkin lymphoma are staged the same. Stage 3 lymphoma means that cancer is present on both sides of the diaphragm in one or more lymph node groups, in the spleen or in a location near a lymph node area, according to the National Cancer Institute.

Hodgkin and non-Hodgkin lymphoma differ in behavior and spread, which means that different treatment options are required for each lymphoma type, says Cancer Research UK. Health professionals can differentiate between the two lymphomas using several different tests.

Hodgkin lymphoma, also called Hodgkin disease, is a specific type of lymphoma that occurs in the body’s white blood cells and is characterized by the presence of Reed-Sternberg cells, states the American Cancer Society. Non-Hodgkin lymphoma is a general term for different types of lymphomas that develop from the body’s white blood cells, such as T-cells, B-cells and natural killer cells, according to Mayo Clinic. This type of lymphoma is more common than Hodgkin lymphoma, according to the American Society of Clinical Oncology.