Is It Safe to Stop Synthroid Suddenly?

Stopping Synthroid suddenly without medical supervision can result in serious consequences, according to Dr. Martin Wodi. As Synthroid is prescribed to replace thyroid hormones in people with dysfunctional thyroid glands, stopping the medication abruptly can lead to hypothyroid symptoms, such as depression, aches and pains, cold sensitivity, weight gain, dry skin and constipation. RxList advises patients against stopping Synthroid suddenly even if they feel well.