Each sheet of drywall typically requires 32 screws to secure it properly and ensure that the installation complies with local building codes. For a 4-by-8-foot sheet, this equates to four rows of eight screws, if the joists or studs are evenly spaced.
Each sheet of drywall should be hung with a screw about every 12 inches. This translates to one screw for each square foot of area to be covered, not taking into account the lack of screws needed where windows, doors and fixtures are located. A pound of screws typically contains around 320 pieces, so it is only a matter of calculating the area of the project to determine how many pounds will be needed.