What Does Low TSH and Normal T3 and Normal T4 Mean?

By Staff WriterLast Updated Apr 2, 2020 12:05:15 AM ET

Some patients with low TSH combined with normal levels of T3 and T4 eventually develop overt thyroid disease, but clinical assessment and management needs to be tailored to each patient, according to Thyroid Foundation of Canada. Typically, low or suppressed TSH combined with high levels of T4 or T3 indicates hyperthyroidism. Abnormally high TSH in conjunction with low T4 is usually a sign of hypothyroidism.