How Long Does Metoprolol Stay in Your System?

Metoprolol stays in the system up to 28 hours. This medication has a half-life of 3 to 4 hours, as stated by Novartis.

Metoprolol is a prescription medication beta-blocker. It is typically given to patients with heart problems, such as hypertension, high heart rate and blood pressure.

There are some potential side effects that patients taking Metoprolol can develop, including short term memory loss, hypotension, confusion, cardiovascular, hematological and allergic reactions, as stated by When patients experience the more severe adverse effects, doctors may want to take them off of Metoprolol and put them on a different medication, or reduce the dosage.

It may take a little over a day for the medication to be completely out of the patient’s system. This is based on a half-life of 4 hours and about seven half-life cycles for the body to eliminate over 99 percent of the medication. However, doctors may opts to use only five half-life cycles to calculate how long it takes for the body to eliminate a medication, as stated by Weil Medical College of Cornell University. This is because over 95 percent of the medication would be eliminated by the body after five cycles.

If the patient’s body has a hard time metabolizing the medication, it can take longer to eliminate completely. For Metoprolol, the increased half-life would be 9 hours. This means it would take up to 63 hours to get completely out of the system.