What Happens If You Go Out in the Sun While Taking Bactrim DS?

By Staff WriterLast Updated Apr 15, 2020 8:38:38 PM ET
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Going out in the sun while taking Bactrim DS can cause a rash, itching, redness and other skin discolorations, according to Daily Strength. The combination of sulfonamide and trimethoprim present in Bactrim DS increases the skin's sensitivity to the sun and makes it important for people taking Bactrim DS to avoid direct sun exposure and take the necessary precautions to prevent an adverse reaction.