What Is the Difference Between Humalog and Humulin?

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Humalog is a rapid-acting insulin treatment for diabetes, while Humulin is short-acting, according to Drugs.com. Humalog has an on-set time of 15 minutes, a peak effectiveness at 1 1/2 hours and a duration of two to five hours. Humulin has an on-set time of 30 to 60 minutes, a peak effectiveness between two and five hours and a duration of six to eight hours.

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