Some causes of a burning sensation in the skin on the legs include burns from chemicals or extreme heat, peripheral neuropathy due to specific diseases or conditions, and exposure to poisonous substances that damage the nerves in the skin. Sometimes a leg burning sensation may occur as a result of a life-threatening condition, such as a transient ischemic attack or stroke, notes Healthgrades.
The physical causes of a burning sensation in the skin of the leg include exposure to cold, burns and pressure on a nerve, explains Healthgrades. The diseases that can cause a burning sensation in the leg include alcoholic neuropathy, where there is nerve damage associated with excessive alcohol consumption; Guillain-Barr Syndrome, which is an auto-immune disorder; shingles; and Meralgia parestheticas. Meralgia paresthetica is a condition that causes a burning feeling in the outer thigh as a result of too much pressure or damage to one of the nerves in the leg, notes WebMD. It is also referred to as Bernhardt-Roth syndrome.
As a serious disease can cause the sensation of leg burning, it is important to seek treatment in order to avoid serious complications and permanent damage. Potential complications that can arise from this symptom include brain damage, chronic pain, loss of a limb and permanent nerve damage, notes Healthgrades.