What Causes Blue Sclera?

By Staff WriterLast Updated Apr 9, 2020 4:04:03 AM ET

Blue sclera, or a blue tint to the white's of a patient's eyes, can be caused by the disease osteogenesis imperfecta, according to Medline Plus. Osteogenesis imperfect is a congenital disease that is most commonly caused by a defect in the gene that codes for type 1 collagen.