Can I Take Tylenol and Sudafed Together?

By Staff WriterLast Updated Apr 3, 2020 8:02:52 PM ET

It is safe to take Tylenol and Sudafed together, according to WebMD. However, certain drugs combine pseudoephedrine, which is the generic ingredient in Sudafed, and acetaminophen, found in Tylenol. If this is the case, additional Sudafed or Tylenol should not be taken in order to avoid an overdose.