What Can Cause Red Spots on the Palms of the Hands?

By Staff WriterLast Updated Mar 25, 2020 4:32:33 AM ET

According to WebMD, red spots on the palms of the hands are a common symptom of psoriasis, a skin condition in which the skin cells rapidly multiply, resulting in plaques and patches on the skin. Red spots on the palms can also be caused by hand, foot and mouth disease or by endocarditis.