Is It Bad to Drink Alcohol While on a Z-Pak of Antibiotics?

By Staff WriterLast Updated Apr 11, 2020 6:32:21 AM ET

It is best to avoid alcohol while taking a Z-Pak, according to Healthline. Azithromycin, the antibiotic in a Z-Pak, is filtered from the body through the liver. Drinking alcohol while taking this medication puts extra stress on the liver and can lead to liver damage.