Creams and lotions containing 40 percent urea are used to treat skin disorders such as dermatitis, psoriasis, eczema, and dry, flaky skin. Urea creams work by removing hardened, scaly bits of dead skin and promoting the healing of underlying areas.
Urea cream also contains emollients, such as mineral oil and petroleum, to help distribute the urea, keep it on the skin and protect the area from further damage. This cream is also used to treat ingrown and damaged nails. Urea cream is not for internal use, and care should be taken when applying it to areas around the mouth or eyes.