There's evidence of antibiotic use since ancient times. Many civilizations used topical application of mouldy bread, with many references to its beneficial effects arising from ancient Egypt, China, Serbia, Greece and Rome. The first person to directly document the use of moulds to treat infections was John Parkinson (1567–1650).
The first of the “modern day” antibiotics were sulphur containing compounds – the first sulphur containing drug, prontosil rubrum, was used to treat human infection in 1935.
For example, anecdotes about the antibiotic-like properties of red soils in Jordan that were used historically (and are still being used as an inexpensive alternative to pharmaceutical products today) for treating skin infections have led to the discovery of a number of antibiotic-producing bacteria and concomitant antibiotic production in ...
Penicillin was the first antibiotic, discovered by Alexander Fleming in 1929, but it was not until the early 1940s that its true potential was acknowledged and large scale fermentation processes were developed for the production of antibiotics. They have been used to treat a wide variety of often dangerous illnesses caused by bacteria.
Antibiotics transformed medicine. The discovery of antibiotics began by accident. On the morning of September 3rd, 1928, Professor Alexander Fleming was having a clear up of his cluttered laboratory. Fleming was sorting through a number of glass plates which had previously been coated with staphyloccus bacteria as part of research Fleming was doing.
Antibiotics are medications taken to fight infections caused by bacteria. When they first became available during World War II (1939-1945), antibiotics were called "wonder drugs" because of their stunning record for safety and effectiveness.
The Golden Age of antibiotics. The first antibiotics were prescribed in the late 1930s, beginning a great era in discovery, development and prescription. Bacterial infection, as a cause of death ...
The history of antibiotics. Antibiotics have been used for millennia to treat infections, although until the last century or so people did not know the infections were caused by bacteria. Various moulds and plant extracts were used to treat infections by some of the earliest civilisations – the ancient Egyptians, for example, applied mouldy ...
But supplies at first were limited, and priority was given to military use. Dr. Chester Keefer of Boston, Chairman of the National Research Council's Committee on Chemotherapy, had the unenviable task of rationing supplies of the drug for civilian use. Keefer had to restrict the use of the drug to cases where other methods of treatment had failed.
During 1940's and 50's streptomycin, chloramphenicol, and tetracycline were discovered and Selman Waksman used the term "antibiotics" to describe them (1942) Sir Alexander Fleming The discovery of penicillin from the fungus Penicillium notatum perfected the treatment of bacterial infections such as, syphilis, gangrene and tuberculosis.