The key difference between crystalloids and colloids is that the colloids contain much larger molecules than that of crystalloids.. Crystalloid and colloid solutions are largely useful for medical purposes. Hence, it is vital to know the difference between crystalloids and colloids so as to decide when to use these solutions.
crystalloid solution: Transfusion medicine A balanced isotonic solution–eg, Ringer's lactate or saline fluid solution, used for volume expansion. Cf Colloid solution .
Otherwise, the choice to use crystalloid versus colloid should be based upon the comorbidities of the patient and the overall clinical picture. When replacing blood loss, you need to administer approximately 3x estimated blood loss volume when using a crystalloid solution.
Crystalloids. The most commonly used crystalloid fluid is normal saline, a solution of sodium chloride at 0.9% concentration, which is close to the concentration in the blood . Ringer's lactate or Ringer's acetate is another isotonic solution often used for large-volume fluid replacement. The choice of fluids may also depend on the chemical ...
However, colloid solutions are less likely to cause oedema than crystalloid solutions. Crystalloids are less expensive, carry little or no risk of anaphylaxis, and pose no problem for vegetarian or vegan patients. However, evidence on any potential harmful effects of crystalloids is inconclusive.
crystalloid: [ kris´tah-loid ] 1. resembling a crystal. 2. a substance whose particles are smaller than those of a colloid , form a true solution, and are therefore capable of passing through a semipermeable membrane , as in dialysis . The physical opposite of a crystalloid is a colloid , which does not dissolve and does not form true solutions.
Crystalloids Are solutes that are easily mixed and dissolve in a solution. The solutes may be electrolytes or nonelectrolytes (dextrose) which are small molecules that flow across the semipermeable membrane, allowing transfer from bloodstream into cells and body tissues.
Crystalloids are aqueous solutions of mineral salts or other water-soluble molecules. Colloids contain larger insoluble molecules, such as gelatin. Blood is a colloid. The most commonly used crystalloid fluid is normal saline, a solution of sodium chloride at 0.9% concentration, which is close to the concentration in the blood .
Isotonic Solutions. If a crystalloid solution is very close to the normal body fluid composition, this is known as an isotonic solution. Isotonic solutions are those that mimic the body's fluid ...
Both crystalloids and colloids increase intestinal blood flow and systemic arterial pressure; however, colloids may have a longer duration of effect.Colloids also result in a net movement of fluid from the intestinal lumen to the blood, whereas crystalloids can exacerbate transmucosal fluid movement into the intestinal lumen.