Sometimes night cramps occur without any identifiable causes, but they generally tend to represent muscle fatigue or nerve problems, according to Mayo Clinic. Known causes for night leg cramps include medications, metabo... More » Health Pain & Symptoms

Legs may cramp at night for a variety of reasons, including too much exercise, sitting for a long time or sleeping in an awkward position, according to WebMD. Underlying conditions of night leg cramps include pregnancy, ... More »

Nighttime leg cramps are the result of sudden muscle tightening for which the cause is not always known, according to Mayo Clinic. These harmless spasms are usually related to overuse of muscles or nerve problems. More » Health

Chronic fatigue syndrome and hypothyroidism are two conditions that cause muscle soreness not related to trauma or other explanations, notes Mayo Clinic. People with chronic fatigue syndrome may experience other symptoms... More »

The effectiveness of treatment for leg cramps depends on the underlying cause of the cramp, but most cramps respond well to self-treatment, notes WebMD. Many are also easy to prevent by drinking plenty of fluids and avoi... More » Health Pain & Symptoms

Thigh cramps at night have various causes, including unknown reasons, muscle fatigue, nerve problems and drugs, according to Mayo Clinic. In rare cases, diseases such as peripheral artery disease, diabetes and spinal ste... More » Health Pain & Symptoms

Some causes of calf muscle cramps are circulatory problems, a deficiency in certain minerals, overheating the body, dehydration, medications, compressed or pinched nerves and muscle strain. A medical condition, such as p... More »