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Oral intake and topical administration of vitamin D, particularly vitamin D3, is likely safe in daily doses up to 4,000 IU a day, states Mayo Clinic. Most people will not experience adverse side effects from a 2,000 IU dose.


People with significant vitamin D deficiency benefit from vitamin D in dosages as significant as 50,000 IU each week for a short period of time, but doctors recommend a lower dosage over a longer period of time, notes U.S. News. Short weekly regimens with 50,000 IU dosage don't cause toxicity.


Benefits of using 50,000 international units of vitamin D-3 include supporting healthy growth and development of bones, facilitating enhanced immune function and maintaining cardiovascular health. Using vitamin 50,000 international units of vitamin D-3 also encourages a greater sense of well-being,


The abbreviation "IU" on vitamin labels means "international units." It is a standard used by the scientific community to measure the amount of fat-soluble vitamins such as A, D and E in a capsule or tablet.


A 1,000 international unit dose of vitamin D is 25 micrograms, which converts to approximately 0.03 milligrams, according to Mayo Clinic. As of 2010, the recommended daily allowance of vitamin D is 600 international units for people ages 1 to 70 years or for women who are pregnant or breast-feeding.


First, convert the 4,000 IU of vitamin D to micrograms by dividing 4,000 by 40 for a total of 100 micrograms, then convert micrograms to milligrams by dividing 100 by 1,000 for a total of 0.10 milligrams. The abbreviation IU stands for International Unit, and it is an internationally recognized meth


The most common side effects of vitamin D include fatigue, weakness, dry mouth or a metallic taste in the mouth, loss of appetite, nausea and vomiting, according to WebMD. Most people do not experience side effects with vitamin D, unless they take too much.


The Vitamin D Council recommends between 5,000 and 10,000 IU of vitamin D daily for adults because their research suggests that this is the optimum amount the body needs for overall good health. Vitamin D is important to support healthy functioning of the heart, lungs, brain, muscles and bones.


Rickets, cardiovascular disease, cognitive issues, asthma, bone pain, muscle weakness and cancer are associated with low levels of vitamin D, according to WebMD. Vitamin D deficiency may also play a role in the development of multiple sclerosis, Type 2 diabetes, hypertension and glucose intolerance.


The oral adult dose of vitamin D-3, or cholecalciferol, used to treat vitamin D insufficiency is 400 to 1000 international units, or IU, once a day, according to Drugs.com. The usual dose of vitamin D-3 cholecalciferol used to treat adults with a vitamin D deficiency is 1000 IU once daily.