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Explore the what's and why's of gene therapy research, includingan in-depth look at the genetic disorder cystic fibrosis and how gene therapy could potentially be used to treat it.


Students will state their own opinion about who should have access to gene therapies, how gene therapies should be used, and to what extent the government should regulate gene therapies. Students will examine and state the personal beliefs that shape their opinions about the various aspects of gene therapy.


gene therapy, including information about viral vectors, the associated risks and challenges, and additional resources. • Article: If Gene Therapy is the Cure, What is the Disease ? by Arthur L. Caplan,


The Genetic Science Learning Center at the University of Utah provides an interactive introduction to gene therapy and a discussion of several diseases for which gene therapy has been successful. The Centre for Genetics Education provides an introduction to gene therapy, including a discussion of ethical and safety considerations.


In 2017, the FDA approved the first gene therapy for an inherited ocular disease. The SCTM treatment could be the next such therapy as physicians and researchers embrace personalized medicine. “The dream for the future is to ultimately treat patients based solely on their genetics,” said Hageman.


Gene therapy treats disease by introducing new genetic material. Often, the therapy provides instructions for making a beneficial protein. There are five distinct strategies deployed in gene therapy. - Gene addition supplements the cell with a working copy of the mutated gene or a new gene, and it is a common approach in gene therapy.


Gene therapy is designed to introduce genetic material into cells to compensate for abnormal genes or to make a beneficial protein. If a mutated gene causes a necessary protein to be faulty or missing, gene therapy may be able to introduce a normal copy of the gene to restore the function of the protein.

www.troup.org/userfiles/929/My Files/Science/HS Science/Biology/Unit 2 - Genetics...

Exploring Gene Therapy webquest. 3. Assessment Suggestions • Use the completed Exploring Gene Therapy webquest as an assessment. 4. Extensions • Please see Additional Resources for more gene therapy activities. 5. Common Misconceptions • Students sometimes think that gene therapy replaces a faulty gene with a functional copy.


In particular, the Rocky Mountain States have the highest age-adjusted suicide rates in the US, and Utah is consistently in the top ten. These statistics, and several unique data resources in Utah, have contributed to the development of the Utah Suicide Genetics Project. Studying the genetics of suicide is a daunting task.