Web Results

www.mayocliniclabs.com/test-catalog/Clinical+and+Interpretive/83397

RNA polymerase III is a complex, 16-subunit enzyme directing transcription of small, stable nontranslated RNA genes: tRNA, 5S rRNA, Alu RNA, U6 snRNA, and 7SK snRNA genes. The immunodominant epitope for autoantibodies with anti-RNA polymerase I/III specificity has been identified on the RNA polymerase-specific subunit RPC155.(4)

ltd.aruplab.com/tests/pub/2001601

RNA polymerase III IgG antibody occur in about 11-23 percent of SSc patients, and typically in the absence of anti-centromere and anti-Scl-70 antibodies. A negative result indicates no detectable IgG antibodies to the dominant antigen of RNA polymerase III and does not rule out the possibility of SSc.

neurology.testcatalog.org/show/RNAP

RNA polymerase III is a complex, 16-subunit enzyme directing transcription of small, stable nontranslated RNA genes: tRNA, 5S rRNA, Alu RNA, U6 snRNA, and 7SK snRNA genes. The immunodominant epitope for autoantibodies with anti-RNA polymerase I/III specificity has been identified on the RNA polymerase-specific subunit RPC155.(4)

testdirectory.questdiagnostics.com/.../19899/rna-polymerase-iii-antibody?cc=MASTER

RNA Polymerase III Antibody. Test Code. 19899. CPT Code(s) 83516. Print. Test Code. 19899. CPT Code(s) 83516. Not offered in Quest Infectious Disease Inc. - San Juan Capistrano, CA. Please provide SERVICE AREA INFORMATION to confirm Test Code for the lab that services your account or to find available tests you can order.

www.ncbi.nlm.nih.gov/pmc/articles/PMC2430219

To evaluate the analytical performance of an ELISA for the detection of anti-RNA polymerase III antibody (ARA) and to assess IIF as a method for identifying this antibody. Methods. A commercially available ELISA was used to assess the presence of ARA in sera from 1018 SSc patients.

www.sciencedirect.com/science/article/pii/S1568997209000342

Anti-RNA polymerase III antibody in SSc is a marker of rapid onset of disease and skin thickening progression. Acknowledgment. This work was supported by the kind help of Instrumentation laboratory SpA (Milan, Italy) and INOVA Diagnostics, Inc (San Diego, CA, USA).

www.ncbi.nlm.nih.gov/pmc/articles/PMC3978927

Results. Among 2,177 patients with SSc, 7.1% had a history of cancer, 26% were positive for anticentromere antibodies (ACAs), 18.2% were positive for anti-Scl-70 antibodies and 26.6% were positive for anti-RNA polymerase III (anti-RNAP) antibody.

en.wikipedia.org/wiki/RNA_polymerase_III

In eukaryote cells, RNA polymerase III (also called Pol III) transcribes DNA to synthesize ribosomal 5S rRNA, tRNA and other small RNAs. The genes transcribed by RNA Pol III fall in the category of "housekeeping" genes whose expression is required in all cell types and most environmental conditions.

sclerodermainfo.org/faq/scleroderma-antibodies

With centromere antibodies, pulmonary artery hypertension is a significant risk, but usually later in the disease process. As indicated in Table 2 below, the three most common antibodies found in patients with systemic scleroderma are Scl-70, centromere, and RNA Polymerase III.

www.wieslab.com/diagnostic-services/index.php?headId=72&pageId=116&subId=116&...

RNA polymerase (RNAP) is a multiprotein complex (> 500kDa) consisting of 8-14 subunits. RNA polymerases are divided into RNA polymerases I, II and III. Antibodies against RNA polymerase are markers for systemic sclerosis and can be detected in approximately 20% of patients.