Single fructosamine measurements should be interpreted in the light of clinical signs of diabetes, body weight and blood glucose concentration. In general, the closer the fructosamine concentration is to the reference range for healthy dogs and cats, the better the glycemic control.
Glucose and fructosamine testing in pets allow a veterinarian to monitor a diabetic cat or dog. Here's what you need to know about these important blood tests.
The higher the serum fructosamine concentration, the higher the blood glucose levels have been over the lifespan of the albumin protein, which is 1-2 weeks in dogs. The serum fructosamine concentration is meant to reflect the blood glucose concentration level over a 7-10 day period prior to testing.
Fructosamine should be within near-normal values if your pet's diabetes is under good control. The test is also useful for pets that live in out-of-the-way places. The level of blood glucose in samples goes down proportionately to the length of time it takes to get the sample to a laboratory to be run.
Because fructosamine is an indicator of the average glucose levels over the prior 2-3 week period, animals with insulin overdose and Somogyi rebound can have an increased, decreased or normal fructosamine value, depending on the relative amount of time spent in the hypoglycemic state versus in the rebound hyperglycemic state.
Fructosamine levels that are elevated indicate that the blood glucose level has been elevated for most of the prior few weeks. Fructosamine levels help us to adjust the insulin dose. In general, if a fructosamine level is low then the insulin dose is likely too high. If the fructosamine level is high it could mean that the insulin is under ...
Fructosamine is formed in dogs’ and cats’ (and people’s) livers by combining the protein albumin with a molecule of glucose.Fructosamine is formed in proportion to glucose levels: pets with unregulated diabetes mellitus have high glucose levels, and, thus, have high fructosamine levels.
The half-life of fructosamine molecules is directly dependent on the half-life of serum proteins, primarily albumin, which is generally 2-3 weeks in dogs and cats. Therefore, fructosamine is an indicator of the blood glucose concentration over a longer period of time than a single blood glucose measurement (which reflects the glucose ...
Serum fructosamine concentrations were measured in 11 untreated hypothyroid dogs with normal serum glucose and serum protein concentrations. The fructosamine level ranged between 276 and 441 ...
The normal reference range for serum fructosamine is determined in healthy dogs and cats with persistently normal blood glucose concentrations. interpretation of serum fructosamine in a diabetic dog or cat must take into consideration the fact that hyperglycemia is common, even in well-controlled diabetic animals..