A serum fructosamine (a glycated protein) level, similar to a hemoglobin A1c level, enables assessment of long-term glycemic control in patients with diabetes mellitus. Normal values vary in relation to the serum albumin concentration and are 200-285 µmol/L, when the serum albumin concentration level is 5 g/dL.
Fructosamine testing may be used to help people with diabetes monitor and control their blood glucose levels in cases where the A1c test cannot be used and/or a shorter-term monitoring window is desired. The level of fructosamine in the blood is a reflection of glucose levels over the previous 2-3 weeks.
The fructosamine test is similar to the hemoglobin A1c test, but it is not as commonly used.The main difference between the two tests is that the fructosamine test measures your average blood glucose level over the past two or three weeks, while the A1c test is a measurement average of your blood sugar over the past two to three months. In addition, the fructosamine test measures glycated ...
3) High Fructosamine Levels are Associated with Kidney Disease. In a study of more than 12k people, those with high fructosamine levels were more likely to have chronic kidney disease compared to people with normal levels . 4) High Fructosamine Levels Increase Recurrent Pregnancy Loss Risk
Fructosamine is available as laboratory test which can be used as an alternative to HbA1C. The normal range for Fructosamine is 258 - 317 μmol, equivalent to an HbA1C of 6-7%.. Formulae relating Fructosamine to HbA1c have been developed in both the UK and US, as follows: Fructosamine = (A1C-1.61) x 58.82 Limitations of HbA1c
Single fructosamine measurements should be interpreted in the light of clinical signs of diabetes, body weight and blood glucose concentration. In general, the closer the fructosamine concentration is to the reference range for healthy dogs and cats, the better the glycemic control.
In a similar way to hemoglobin A1c testing (which measures the glycation of hemoglobin), fructosamine testing determines the fraction of total serum proteins that have undergone glycation (the glycated serum proteins). Since albumin is the most abundant protein in blood, fructosamine levels typically reflect albumin glycation.
A normal fructosamine level may indicate that a diabetic has good diabetic control and that the current treatment plan is effective for the individual. Likewise, a trend from high to normal fructosamine levels may indicate that changes to a person's treatment regimen have been effective.
Understanding the Fructosamine Blood Test Results The levels of fructosamine in the blood are a reflection of the overall glucose levels that someone is experiencing. That’s why this blood test is often used to help someone who has a confirmed diagnosis of diabetes mellitus to control their glucose levels.
Just as with HbA1c, a high fructosamine level indicates that blood glucose has been elevated, and a normal fructosamine level indicates good blood glucose control. Ketones. If your blood glucose or insulin level is so low that your body cannot use glucose as an energy source, the body mobilizes another source of energy: fats.