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www.pharmatutor.org/pharmacology/general-pharmacology/metabolism.html

Metabolism (biotransformation) Same like metabolism of carbohydrate, protein, lipids, the drug will metabolized by enzymes present in the body. The conversion of lipid soluble substances or drug in to water soluble compound by enzymatic reaction is called as bio-transformation. It involves alteration of drug molecule. Table of Content Metabolising Enzymes Chemical Phases The

ukdiss.com/examples/metabolism-of-drugs.php

Metabolism of drugs is a complex and major process within the body, occurring primarily in the liver. The aim of metabolism is to make the drug more polar to enable excretion via the kidneys. The basic understanding of drug metabolism is paramount to ensure drug optimisation, maximum therapeutic benefits and a reduction in adverse effects.

www.msdmanuals.com/home/drugs/administration-and-kinetics-of-drugs/drug-metabolism

Most drugs must pass through the liver, which is the primary site for drug metabolism. Once in the liver, enzymes convert prodrugs to active metabolites or convert active drugs to inactive forms. The liver’s primary mechanism for metabolizing drugs is via a specific group of cytochrome P-450 enzymes.

www.pharmaguideline.com/2014/08/absorption-distribution-metabolism-and...

Drug Metabolism: Termination of drug effect, also termed as drug elimination involves two processes; metabolism, mainly in the liver and kidneys and excretion of unchanged drug and /or its metabolites by the kidneys, gut, lungs, sweat glands, breasts and salivary glands. Some drugs are excreted from the body unchanged, but the majority of them ...

www.partone.lifeinthefastlane.com/metabolism.html

Metabolism. Describe the mechanisms of drug clearance and metabolism. Removal of drug from the body requires either: Metabolism of active drug to an inactive substance Typically by the liver, but other organs (kidney, lungs) also metabolise some substances. Excretion of active drug Often by the kidneys, but may also be in bile, or exhaled.

www.technologynetworks.com/diagnostics/blog/the-absorption-distribution...

Drug metabolism. There were no abnormal changes in liver function indexes in the elderly, but the activity of drug metabolism enzyme in the liver is decreased so that the half-life of the drug is prolonged. Also, the age associated reduction of parenchymal cells in the liver and a reduction of liver blood flow affects the ability of the liver ...

rarediseases.info.nih.gov/diseases/12906/cyp2c19-related-poor-drug-metabolism

CYP2C19-related poor drug metabolism is a condition in which the body is unable to properly process certain types of medications such as clopidogrel, mephenytoin, omeprazole, and/or proguanil.As a result, these medications are less effective in affected people who are treated with them. The condition is caused by changes (mutations) in the CYP2C19 gene and is inherited in an autosomal ...

www.mayoclinic.org/healthy-lifestyle/weight-loss/in-depth/metabolism/art-20046508

Products that claim to speed up your metabolism are often more hype than help, and some may cause undesirable or even dangerous side effects. Dietary supplement manufacturers aren't required by the U.S. Food and Drug Administration to prove that their products are safe or effective, so view these products with caution.

www.drugs.com/drug-class/metabolic-agents.html

Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Data sources include IBM Watson Micromedex (updated 2 Nov 2020), Cerner Multum™ (updated 2 Nov 2020), ASHP (updated 23 Oct 2020 ...

www.aafp.org/afp/2009/1201/p1254.html

Although many medications are processed through phase I hepatic metabolism, warfarin (Coumadin) is one of the few to demonstrate a difference in dosage requirement based on sex.