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Some symptoms of end-stage liver cancer include worsening jaundice, drowsiness and confusion, according to Merck Manuals. Fatigue, pain, changes in appetite and difficulty breathing are additional symptoms of end-state cancer, reports the American Cancer Society.


Stages III and IV are the final stages of liver cancer. During these stages, there may be multiple cancerous tumors and a spread of cancer to blood vessels beyond the liver to lymph nodes or to other body parts, such as the bones or the lungs, according to Cleveland Clinic.


Multiple factors, including the size of the cancer, how far the disease has spread, the number of lesions, the quality of surrounding tissue, and the overall health of the patient, impact the duration of time between diagnosis to the final stage of liver cancer, explains MedicineNet.com. The five-ye


Liver cancer is difficult to diagnose in early stages, as it often has no symptoms, and it is rare that medical staff are able to feel tumors from outside the body, according to MD Anderson Cancer Center. The tumor's development causes symptoms, but by then the staging is often advanced.


The difference between stage 4 liver cancer and stage 3 liver cancer is that in stage 4A, the cancer has spread to local lymph nodes, reports the American Cancer Society. In the more advanced stage 4B, the cancer has metastasized to distant organs. In stage 3 liver cancer, the cancer has not spread


One symptom of liver cancer is pain in the right shoulder blade or in the abdomen, according to the American Cancer Society. A person who is suffering from late-stage liver cancer might have chronic cirrhosis or hepatitis, which can make a person feel worse than usual.


The four stages of liver disease are inflammation, fibrosis, cirrhosis and liver failure, according to the American Liver Foundation. Whether the liver is infected, injured by toxins such as alcohol or chemicals, or under attack from a patient's own immune system, liver disease progresses in much th


Symptoms of stage 4 liver disease include vomiting, diarrhea and fatigue caused by reduced blood flow due to permanent liver scarring. Patients with stage 4 liver disease require immediate medical treatment to prevent death, according to Florida Hospital.


Symptoms of liver cancer include loss of appetite, unexplained weight loss, pain and swelling in the abdomen, vomiting, nausea, fatigue, chalky stools and yellowing of the whites of the eyes and skin. However, early stages of liver cancer often present no symptoms, as stated by Mayo Clinic.


In the early stages of primary liver cancer, people may not have any major symptoms, states the American Cancer Society. It is in the later stages that symptoms occur and can include abdominal pain in the upper right quadrant of the stomach, spleen or liver enlargement, jaundice, loss of appetite, w