Web Results

www2.le.ac.uk/projects/vgec/healthprof/topics/patterns-of-inheritance/patterns-of-inheritance-conditions

These disorders are the result of a single defective gene on the autosomes. They are inherited according to Mendel's Laws (Mendelian disorders). The mutation ...

jmg.bmj.com/content/57/11/725

The use of PGS as a predictive biomarker is being explored in a number of different disease areas, including cancer,3 4 psychiatric disorders,5–7 metabolic  ...

journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1002973

Oct 11, 2012 ... For polygenic diseases, no single risk factor has a large effect in ... we started from a list of curated genome-wide associations compiled by the ...

jamanetwork.com/journals/jamacardiology/fullarticle/2760785

Feb 12, 2020 ... Cardiovascular disease events were defined by diagnosis codes from the International Classification of Diseases, Ninth Revision and ...

wiki.groenkennisnet.nl/display/TAB/Chapter+4.3+Collecting+phenotypes%2C+monogenic+and+polygenic+traits

Some polygenic traits such as occurrence of disease are on binary scale: sick ( e.g. 1) or not (e.g. 0).

www.cdc.gov/genomics/events/risk_scores_2020.htm

In recent years, findings from genome-wide association studies (GWAS) have been used to generate polygenic risk score models for various complex diseases .

rarediseases.org/rare-diseases/retinitis-pigmentosa

Some forms of RP can be associated with deafness, obesity, kidney disease, ... “ polygenic” disorders), RP is the most common cause of inherited visual loss.

www.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082017000200233

Based on these concepts, a polygenic or multifactoral pattern of inheritance used to be ... A full accurate and updated list of ASD risk genes, including scientific ...

www.frontiersin.org/articles/10.3389/fdgth.2020.00014/full

Aug 11, 2020 ... Due to the polygenicity of AD, polygenic risk scores (PRS) have shown ... the resulting list of SNPs is very likely to be different for different input ...

www.genengnews.com/insights/gene-therapys-renaissance

Oct 2, 2020 ... ... practical solution for a growing list of previously incurable diseases. ... Now, gene therapy is taking on more complex, multigene diseases such as ... for mor...