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pubmed.ncbi.nlm.nih.gov/31492155

Idiopathic pulmonary fibrosis (IPF) is a progressive disease with a dismal prognosis. The average life expectancy of untreated patients with IPF is only 3 to 4 years. Decline in forced vital capacity (FVC) in patients with IPF appears to be almost linear, with patients with well-preserved FVC at bas …

www.fda.gov/media/91396/download

1 Since this date, two drug products have been approved by FDA for the treatment of IPF. These include Ofev These include Ofev (nintedanib) and Esbriet (pirfenidone), both approved October 15, 2014.

medicalxpress.com/news/2019-09-treatment-pulmonary-fibrosis.html

In this study, the teams investigated whether drugs called therapeutic antibodies could reverse the process of lung fibrosis, as IL-11 was found to be crucial to the progression of IPF.

medicalxpress.com/news/2019-07-treatment-idiopathic-pulmonary-fibrosis.html

More than 50,000 people in the U.S. die from idiopathic pulmonary fibrosis (IPF) each year. IPF is a type of lung disease that results in fibrosis, or scarring, of the lungs.

respiratory-research.biomedcentral.com/articles/10.1186/s12931-019-1161-4

Idiopathic pulmonary fibrosis (IPF) is a progressive disease with a dismal prognosis. The average life expectancy of untreated patients with IPF is only 3 to 4 years. Decline in forced vital capacity (FVC) in patients with IPF appears to be almost linear, with patients with well-preserved FVC at baseline experiencing the same rate of decline in FVC as patients with more advanced disease.

en.wikipedia.org/wiki/Idiopathic_pulmonary_fibrosis

Idiopathic pulmonary fibrosis (IPF) is a type of chronic scarring lung disease characterized by a progressive and irreversible decline in lung function. Symptoms typically include gradual onset of shortness of breath and a dry cough. Other changes may include feeling tired, and abnormally large and dome shaped finger and toenails (nail clubbing). ...

www.webmd.com/lung/what-is-idiopathic-pulmonary-fibrosis

Idiopathic pulmonary fibrosis (IPF) is a rare lung disease that causes scar tissue to grow inside your lungs. Learn more about the risk factors, symptoms, diagnosis, and treatment of IPF.

www.healthline.com/health/managing-idiopathic-pulmonary-fibrosis/ipf-vs-copd

IPF is a rare disease, affecting an estimated 100,000 people in the United States, with 34,000 new cases diagnosed each year. COPD is much more prevalent and is considered to be a major U.S ...

www.blf.org.uk/support-for-you/idiopathic-pulmonary-fibrosis-ipf/treatment

Treatment for IPF. Treatment can include medication to slow the rate of scarring (pirfenidone and nintedanib) and treatment of your symptoms. You should be treated at a specialist centre, or by a team that comes from the specialist centre to your local hospital, and have hospital appointments every 3-6 months.

trials.pulmonaryfibrosis.org

Phase 1: Studies that emphasize safety and how the drug is metabolized and excreted in humans. Phase 2: Studies that gather preliminary data on effectiveness (whether the drug works in people who have a certain disease or condition) and additional safety data. Phase 3: Studies that gather more information about safety and effectiveness by studying different populations and different dosages ...